I'll admit that I enjoyed Ed, Edd n Eddy as a kid. It wasn't the best of the Cartoon Network shows (that would be either Dexter's Lab or Courage the Cowardly Dog) and at times a little TOO meanspirited, but the rubbery animation was pretty good and it had alot of cartoon gags that I liked.
The show's creator was Danny Antonucci, an animator based in Canada. He actually made a name first in the independent animation community with a short called Lupo the Butcher, which was produced by Marv Newland (Bambi Meets Godzilla) at his International Rocketship Limited studio in Vancouver.
Unlike EEE, this is very much not a kid-friendly cartoon. Which is apparently the point, according to an interview with Antonucci where he said he was tired of animation being seen as kids stuff, resulting in the production of the cartoon.
Of course now there's a whole slew of adult cartoons, but Lupo was part of the first that sparked the trend in the first place.