Ah, glad to see this again.
One of the lesser known Osamu Tezuka series was "Goku's Big Adventure", which took over Astroboy's timeslot after that show got cancelled. It only lasted 39 episodes, but the show has charm. It was unusual from Tezuka in that it was very gag-driven, where nothing was taken seriously.
Possibly the most craziest was episode 4, which was directed by the late Osamu Dezaki. It was up on YouTube with English subs few years ago, but it got removed. However someone recently uploaded the entire series dubbed in Italy. It'll do for now, I guess.
Here you go.